This study investigates the subseasonal variability of anticyclonic Rossby wave breaking (AWB) and its impacts on atmospheric circulations and tropical cyclones (TCs) over the North Atlantic in the warm season from 1985 to 2013. Significant anomalies in sea level pressure, tropospheric wind, and humidity fields are found over the tropical–subtropical Atlantic within 8 days of an AWB activity peak. Such anomalies may lead to suppressed TC activity on the subseasonal time scale, but a significant negative correlation between the subseasonal variability of AWB and Atlantic basinwide TC activity does not exist every year, likely due to the modulation of TCs by other factors. It is also found that AWB occurrence may be modulated by the Madden–Julian oscillation (MJO). In particular, AWB occurrence over the tropical–subtropical west Atlantic is reduced in phases 2 and 3 and enhanced in phases 6 and 7 based on the Real-Time Multivariate MJO (RMM) index. The impacts of AWB on the predictive skill of Atlantic TCs are examined using the Global Ensemble Forecasting System (GEFS) reforecasts with a forecast lead time up to 2 weeks. The hit rate of tropical cyclogenesis during active AWB episodes is lower than the long-term-mean hit rate, and the GEFS is less skillful in capturing the variations of weekly TC activity during the years of enhanced AWB activity. The lower predictability of TCs is consistent with the lower predictability of environmental variables (such as vertical wind shear, moisture, and low-level vorticity) under the extratropical influence.